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Bringing more than 20 years of experience in the development of adaptogen supplement technology to people who desire to maintain a healthy, active lifestyle.

The benefits of Adaptogens have been studied for decades. Below are some key studies with adaptogens in both humans and animals that are beneficial in understanding how they work. Adaptogens are known to improve energy, immune support and provide stress relief.

collage of adaptogenic herbs

Ahumada, F., Hancke, J., et al., “Studies on the Effect of Schizandra chinensis on Horses Submitted to Exercise and Maximum Effort.” Phytotherapy Research, Vol. 3, No. 5, 1989.

Bohn, B., Nebe, C.T., and Birr, C., “Flow-cytometric Studies with Eleutherococcus senticosus Extract as an Immunomodulatory Agent.” Arnzmeimitterl-Forschung 35 (10), 1987, pp. 1193-1196.

Bol’shakova, I.V., Lozovskaia, E.L., Sapezhinskii, I.I., “Antioxidant Properties of a Series of Extracts from Medicinal Plants.” Biofizika. 1997 Mar-Apr;42(2):480-3.

Brekhman, I.I., Dardymov, I.V., “New Substances of Plant Origin which Increase Nonspecific Resistance,” Ann Rev Pharmacol, 1969;9:419-430.

Brekhman, I.I., “Eleutherococcus.” Leningrad, 1966.

Collisson, R.J., “Siberian Ginseng (Eleutherococcus senticosus Maxim.)” British Journal of Phytotherapy, Vol. 2, No. 2, 1991

Darbinyan, V., Kteyan, A., Panossian, A., et al, “Rhodiola rosea in stress induced fatigue – a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.” Phytomedicine, 2000; 7:365-371.

Elkin, V.M., Zakharova, N.G., et al., “The Influence of Eleutherococcus on Factors of the Organism’s Resistance,” in: New Data on Eleutherococcus: Proceedings of the 2nd International Symposium on Eleutherococcus (Moscow, 1984), Part 1,
Vladivostok: Far East Academy of Sciences of the USSR, 1986, pp. 159.

Hancke, J., Bugois, R., et al., “Reduction of Serum Hepatic Transamines and CPK in Sport Horses with Poor Performance Treated with a Standardized Schizandra chinensis Fruit Extract.” Phytomedicine, Vol. 3 (3), pp. 237-240.

Kelly, G.S., “Rhodiola rosea: a possible plant adaptogen.” Altern Med Rev, 2001 Jun;6(3):293-302.

Malenkov, A.G., Kolotygina, I.M., “Cell Surface RNA – A Possible Molecular Receptor of Adaptogens.” Biofizika, 1984, Sep-Oct;29(5):814-5.

Ostrovskaya, S.A., Rodina, M.A., et al., “Adaptogens of Vegetable Origin and Immune Response of Human Body,” Clinical Picture, Pathogenesis and Treatment of Influenza and Other Respiratory Diseases. Scientific Research Institute of the Health Ministry of the USSR, Moscow, Medical Pediatrics Institute, Leningrad.

Panossian, A.G., Oganessian, A.S., Ambartsumian, M., Gabrielian, E.S., Wagner, H., Wikman,G., “Effects of Heavy Physical Exercise and Adaptogens on Nitric Oxide Content in Human Saliva.” Phytomedicine, 1999 Mar;6(1):17-26.

Panossian A, Wikman G, Wagner H., “Plant adaptogens. III. Earlier and more recent aspects and concepts on their mode of action.” Phytomedicine, 1999 Oct;6(4):287-300.

Saratikov, A.S., “Rhodiola rosea is a Valuable Medicinal Plant,” Tomsk, 1987, pp. 252.

Stull, C.L., Spier, S.J., et al, “Immunological response to long-term transport stress in mature horses and effects of adaptogenic dietary supplementation as an immunomodulator.” Equine Vet. J. (2004) 36(7)583-589.

Syrov, V.N., Nasyrova, S.S., Khushbaktova, Z.A., “The results of experimental study of phytoecdysteroids as erythropoiesis stimulators in laboratory animals,” Eksp Klin Farmakol, 1997 May-Jun; 60(3): 41-4.

Szolomicki, J., Samochowiec, L., et al, “The influence of active components of Eleutherococcus senticosus on cellular defense and physical fitness in man.” Phytotherapy Res, 2000 May;14(3):225.

Winston, David, Maimes, Steven, “Adaptogens, Herbs for Strength, Stamina, and Stress-Relief,” Healing Arts Press, 2007.

The sources above provide an in-depth scientific view of the multiple phases of research connected with Adaptogens that have been done over the years. Each source should give the reader better insight into how the knowledge of Adaptogens has expanded. This, in turn, leads to a better understanding of how it may provide greater health and homeostasis in the body.


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, mitigate, treat, cure, or prevent any disease.